The original tree is believed to have been the result of a cross between the Saigon and Mulgoba varieties by Wilson Popenoe, grown on his property in Lancetilla on the north coast of Honduras.

[1] Lancetilla was introduced to the United States via South Florida and first received notoriety at the Fairchild Tropical Botanic Garden's 2001 mango festival.

The tree was promoted as a dooryard variety in Florida due to its excellent disease resistance and flavor, and is now widely sold as nursery stock in the state.

A Lancetilla tree is planted in the collection of the Miami–Dade Redland Fruit & Spice Park in Homestead, Florida.

Lancetilla typically matures from August to September in Florida, making it a late season mango.