Laucysteinamide A (LcA) is a marine natural product isolated from a cyanobacterium, Caldora penicillata.

[1] It is structurally related to other marine cyanobacterial metabolites such as somocystinamide A[2] and curacin A, which have inspired extensive investigations into their use as a lead for anticancer therapies.

[3][4][5][6] Its biological activity profile has not been fully evaluated due to decomposition of the natural sample.

[7] This synthetic sample was incorporated into an emulsifier PEG400 and tested for its cytotoxicity against H460 cells.

[7] This work implies that the exceptional antiproliferative activity of somocystinamide A arises from the dimeric nature of its structure and not from the enamide moiety.