The station is in the cutting running from the southern ramp of the City Tunnel.

It consists of two 140 metre-long side platforms that are located directly south of Semmelweisstraße, which crosses the railway tracks here; this street was recently built to connect Kurt-Eisner-Straße with Zwickauer Straße.

MDR stands for Mitteldeutscher Rundfunk, a public broadcaster located near the station.

Leipzig MDR station is served by seven of the ten S-Bahn Mitteldeutschland lines.

Planners hope that the high frequency service and fast journey times will increase passenger capacity on the city's public transport and thus relieve road traffic in the city.