This is a list of investigational antidepressants, or drugs that are currently under development for clinical use in the treatment of depression but are not yet approved.
Specific indications include major depressive disorder, treatment-resistant depression, dysthymia, bipolar depression, and postpartum depression, among others.
Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.
This list was last comprehensively updated in August 2024.
It is likely to become outdated with time.