The Little Watshishou River originates in Lake Gallienne, and flows southwest to enter the Gulf of Saint Lawrence 14 kilometres (8.7 mi) from the village of Baie-Johan-Beetz.

[1] The river flows through the unorganized territory of Lac-Jérôme in Minganie Regional County Municipality.

[11] Joseph Tanguay, originally from Berthier, settled at the Little Watshishou River in 1854.

[13] The Little Watshishou River has icy, often tumultuous waters, with beautiful rapids and waterfalls.

[1] Fish species include Atlantic salmon (Salmo salar), brook trout (Salvelinus fontinalis), American eel (Anguilla rostrata) and ninespine stickleback (Pungitius pungitius).

[14] Atlantic salmon use the last 21 kilometres (13 mi) of the river, up to a waterfall that blocks their way.

In view of the rapidly declining Atlantic salmon population catch-and-release should have been implemented on all rivers apart from northern Quebec.