Lost Creek is an unusual 3-mile (5 km) tributary of the McKenzie River in Lane County, in the U.S. state of Oregon.

It is the lower section of a hydrogeological system, a losing stream, that begins at the base of Collier Glacier in the Cascade Range.

[2] An article in The Ore Bin, a publication of the Oregon Department of Geology and Mineral Industries, explains that White Branch begins at Collier Glacier and follows a glacial trough filled with porous lava.

[3] Limberlost Campground, managed by the United States Forest Service, is along Lost Creek about a mile upstream of the mouth.

Generally open from early May to late September, the campground has campsites, toilets, picnic tables, and fire rings but no drinking water or firewood.