Wain studies how genetic variations impact a patient's risk of developing respiratory disease.
[1][2] Her research makes use of UK Biobank data to better understand the genetic determinants of blood pressure.
[3] Small changes in blood pressure can considerably impact a person's likelihood of developing stroke or cardiovascular disease, and Wain hopes that better understanding the genetics can identify what predicts response to antihypertensive drugs.
[3] In 2017 Wain was awarded a British Lung Foundation Chair in Respiratory Research at the University of Leicester.
[5] In a study of over 400,000 people Wain identified over 100 genetic differences that were likely to increase someone's risk of developing chronic obstructive pulmonary disease.