[5] The protein encoded by this gene is a member of the MAP kinase family.

MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.

Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.

[5] This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 22 is a stub.