5719294178ENSG00000090674ENSMUSG00000004567Q9GZU1Q99J21NM_020533NM_053177NP_065394NP_444407Mucolipin-1 (ML1) also known as TRPML1 (transient receptor potential cation channel, mucolipin subfamily, member 1) is a protein that in humans is encoded by the MCOLN1 gene.
[5] It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels.
TRPML1 is a 65 kDa protein associated with mucolipidosis type IV.
Its predicted structure includes six transmembrane domains, a transient receptor potential (TRP) cation-channel domain, and an internal channel pore.
[7] It is important in lysosome function and plays a part in processes such as vesicular trafficking, exocytosis and autophagy.