MERTK

2DBJ, 2P0C, 3BPR, 3BRB, 3TCP, 4M3Q, 4MH7, 4MHA1046117289ENSG00000153208ENSMUSG00000014361Q12866Q60805NM_006343NM_008587NP_006334NP_032613Proto-oncogene tyrosine-protein kinase MER is an enzyme that in humans is encoded by the MERTK gene.

[5][6][7] This gene is a member of the TYRO3/AXL/MER (TAM) receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain.

Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

This article on a gene on human chromosome 2 is a stub.

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