In enzymology, a mRNA (nucleoside-2'-O-)-methyltransferase (EC 2.1.1.57) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are S-adenosyl methionine and m7G(5')pppR-RNA, whereas its two products are S-adenosylhomocysteine and m7G(5')pppRm-RNA (mRNA containing a 2'-O-methylpurine cap).
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases.
The systematic name of this enzyme class is S-adenosyl-L-methionine:mRNA (nucleoside-2'-O-)-methyltransferase.
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2GA9 and 2GAF.
This EC 2.1 enzyme-related article is a stub.