These hills are composed of quartzites, phyllites and feldspathic sandstones of sedimentary origin.

[1] This plateau has the highest point in Zambia at 2,339-metre (7,674 ft) at Mafinga Central.

As Muyombe is the district capital of the newly formed Mafinga District, any expedition to the Mafinga Hills would be wise to use Muyombe as a starting point (two guesthouses are available).

Besides going through Isoka, Muyombe can also be accessed from the south via Chama, though this road passes briefly through Western Malawi's Vwasa Wildlife Reserve, or from the East via the Malawian town of Bolero on route S104.

As there are no fueling stations near Muyombe, except for in Lundazi, Nakonde, or Rhumpi (Malawi).