Mammillothalamic tract

The mammillothalamic tract is part of the Papez circuit (involved in spatial memory), starting and finishing in the hippocampus.

[2][3][4] It arises from the medial and lateral nuclei of the mammillary bodies, and from fibers that are directly continued from the fornix of the hippocampus.

[3][4][5] Axons divide within the gray matter; the thicker fibres form the MTT while the finer branches descend as the mammillotegmental fasciculus.

[6] The mammillary bodies directly or indirectly connect to the amygdala, hippocampus, and thalami as major structures in the limbic system.

[6] The mammillothalamic tract carries signals from the mammillary bodies via the anterior thalamus to support spatial memory.