Mancozeb

[1] The mixture controls many fungal diseases in a wide range of field crops, fruits, nuts, vegetables, and ornamentals.

In Canada, a mixture of zoxamide and mancozeb was registered for control of the mildew named Gavel as early as 2008.

[2] Mancozeb reacts with, and inactivates, the sulfhydryl groups of amino acids and enzymes within fungal cells, resulting in disruption of lipid metabolism, respiration, and production of adenosine triphosphate.

[4] A major toxicological concern is ethylenethiourea (ETU), an industrial contaminant and a breakdown product of mancozeb and other EBDC pesticides.

It has potential to cause goiter, a condition in which the thyroid gland is enlarged and has produced birth defects and cancer in experimental animals.