It runs from Winnipeg's Perimeter Highway (where it meets with the city's Route 115) east to Elma where it ends at PTH 11.

Also along that stretch of picturesque highway lies the longitudinal Centre of Canada, which is marked on PTH 1 several kilometres south.

PTH 15 becomes undivided and heads due east through farmland to travel straight through the center of Dugald, where it has an intersection with PR 206 and crosses a railroad.

The highway passes through Lewis and Stony Hill as it re-enters farmland as well as the town of Elma.

[1][3] Throughout its length, PTH 15 runs parallel to, and even crosses in Dugald, a Canadian National Railway line.