All games feature Mario as the protagonist, who is often accompanied by one or more playable characters, with the goal of defeating the main antagonist, primarily Bowser.

[5] Recent entries since the release of Sticker Star have been criticized for the removal of original fictional races, the abundance of identical Toads, and the restrictions limiting unique character designs.

The Nintendo 3DS remake of Bowser's Inside Story was AlphaDream's final game before declaring bankruptcy in 2019.

Three months after the declaration, however, Nintendo filed a trademark for the series in Argentina.

[12] The Mario + Rabbids series is co-developed by Ubisoft Milan and Ubisoft Paris and published worldwide by Ubisoft and published in Asia by Nintendo and is a crossover series with the Raving Rabbids franchise, the first being Mario + Rabbids Kingdom Battle for the Nintendo Switch in 2017.