Marisha Ray Huber[Note 1] was born in Mount Washington, Kentucky,[2] the daughter of a dog groomer mother and truck tire salesman father.

[Note 3] Ray arrived in Los Angeles during the Writers Guild strike, causing her difficulty in finding auditions and leading her to support herself financially by canvassing for that year's presidential election.

[11] Ray later described the series as her big break, as it drew a large audience due to the lack of Batgirl media at the time.

[23] She announced her appointment to the post of creative director for Geek & Sundry on July 28, 2017;[24] and her tenure saw the company reach its Twitch subscription peak in January 2018.

[35] In November 2019, Amazon Prime Video announced that they had acquired the streaming rights to this animated series, now titled The Legend of Vox Machina;[36] Ray reprised her role as Keyleth.

[42][43] Madison Durham, for Polygon in February 2022, commented that "Ray has been instrumental in making Critical Role into the sprawling multimedia company that it is today, contributing as the creative lead for shows like All Work No Play, Exandria Unlimited, and more.

[44] A Familiar Problem, a one-page RPG co-written by Ray and Grant Howitt, was released in June 2022; it was published by the Critical Role Productions imprint Darrington Press.

[49] Ray began dating fellow voice actor and Critical Role co-star Matthew Mercer in 2011, and they were engaged in 2016 before marrying on October 21, 2017.

[53] Ray took part in the charity boxing event Creator Clash 2 on April 15, 2023, losing to Haley Sharpe by unanimous decision.