The highway heads east as two-lane undivided Hope Road, which passes the historic home Content and crosses Three Bridges Branch.

[2] Immediately to the east of the US 301 junction, the highway crosses the Centreville Branch of the Northern Line of the Maryland and Delaware Railroad at-grade at the hamlet of Carville.

[1][3] Queen Anne's County constructed with state aid a 9-foot-wide (2.7 m) macadam road from the Centreville Branch of the Philadelphia, Baltimore and Washington Railroad at Carville east to Hope by 1915.

[2] In 1946, Queen Anne's County requested funds for the 3-year post-war construction program to be applied to the 5.5-mile-long (8.9 km) road from Hope to Ingleside.

The county specifically requested the 0.88-mile-long (1.42 km) segment southwest from MD 19 at Ingleside toward Roe be funded for construction during the first year of the program.