MD 405 connects Church Hill and Bridgetown with the central Queen Anne's County community of Price, where the highway intersects U.S. Route 301 (US 301).

MD 405 was extended from Roe to the Caroline County line west of Bridgetown in the early 1940s.

MD 19 heads northwest into the town as Walnut Street and east as Roberts Station Road.

[1][2] The first section of MD 405 to be constructed was a 1-mile-long (1.6 km) stretch of concrete road southeast from the Centreville Branch of the Philadelphia, Baltimore and Washington Railroad at Price in 1929 and 1930.

[10] Caroline County had constructed with state aid the two-span reinforced concrete Mason Branch bridge and a 9-foot-wide (2.7 m) shell road east through Bridgetown in 1914.