[1] Masaka Hospital is located in the central business district of the town of Masaka, approximately 132 kilometres (82 mi), by road, southwest of Mulago National Referral Hospital, in Kampala, Uganda's capital and largest city.

[4] The hospital is designated as one of the 15 Internship Hospitals in Uganda where graduates of Ugandan medical schools can serve one year of internship under the supervision of qualified specialists and consultants.

The official bed capacity of Masaka Hospital is quoted as 330, but often twice that number or more is accommodated.

The work was contracted to Tirupati Development Uganda Limited, and is expected to last about 24 months.

Construction of the five story hospital extension is fully funded by the Government of Uganda.