McCoy Creek is a stream in St. Charles and Warren Counties in the U.S. state of Missouri.

[3] The stream headwaters arise in northeastern Warren County about two miles northwest of Foristell and Interstate 70.

The stream flows to the northeast into St. Charles County crossing under Missouri Route W and US Route 61 northwest of the Flint Hill community.

It enters Big Creek just upstream (east) of the confluence of Big Creek with the Cuivre River.

This article related to a river in Missouri is a stub.