The sixth season of Medium, an American television series, began September 25, 2009, and ended on May 21, 2010.

Within 24 hours of NBC's cancellation, CBS, whose production arm produces the series, renewed the show for a full, 22-episode, sixth season, placing it in the Friday at 9:00 p.m. slot between fellow CBS in-house productions Ghost Whisperer (which had a similar theme to Medium) and Numb3rs.

Upon its return in September 2010, Medium took over the Friday 8 p.m. slot vacated by Ghost Whisperer.

She got to keep her gift because she delayed the surgery from season 5 at the very end to catch Oswaldo Castillo.

The Halloween episode Bite Me is a take on Night of the Living Dead where Allison uses her dream to catch a killer no one would never suspect.