[2][3][4][5] A derivative, medroxyprogesterone acetate (MPA), is used as a medication in humans, and is far more widely known in comparison.

[7] Compared to MPA, medroxyprogesterone is over two orders of magnitude less potent as a progestogen.

[9] In addition to its progestagenic activity, medroxyprogesterone is a weak antiandrogen in vitro on human androgen receptor.

It is closely related to medrogestone as well as other unesterified 17α-hydroxyprogesterone derivatives such as chlormadinone, cyproterone, and megestrol.

[2][3] Medroxyprogesterone is the generic name of the drug and its INNTooltip International Nonproprietary Name and BANTooltip British Approved Name.