Melton Highway (formerly Keilor–Melton Road)[2] links Melbourne's outer north-western suburbs of Melton and Taylors Lakes (western Keilor as the old name suggests), connecting the Western Freeway and Calder Freeway to provide a more-direct route between Ballarat and Melbourne and Essendon airports; it has a Victorian route designation of C754.

The speed limit drops back to 80 km/h approaching Hillside, where the road widens to a four-lane, dual-carriageway and continues east through Sydenham and Taylors Lakes, past Watergardens Town Centre, to eventually terminate at the intersection with Sunshine Avenue in Keilor.

The passing of the Transport Act of 1983[3] (itself an evolution from the original Highways and Vehicles Act of 1924[4]) provided for the declaration of State Highways, roads two-thirds financed by the State government through the Road Construction Authority (later VicRoads).

The passing of the Road Management Act 2004[7] granted the responsibility of overall management and development of Victoria's major arterial roads to VicRoads: in 2004, VicRoads re-declared Melton Highway (Arterial #6040) from Western Freeway in Melton to Sunshine Avenue in Taylors Lakes.

[2] In September 2018, the former level crossing through the Sunbury/Bendigo railway line was replaced by a new 6-lane bridge overpass, with new bike lanes and footpaths on each side, and new paths underneath.