Mesityl bromide is an organic compound with the formula (CH3)3C6H2Br.

It is a derivative of mesitylene (1,3,5-trimethylbenzene) with one ring H replaced by Br.

It is a standard electron-rich aryl halide substrate for cross coupling reactions.

[2] With magnesium it reacts to give the Grignard reagent,[3] which is used in the preparation of tetramesityldiiron.

It is prepared by the direct reaction of bromine with mesitylene:[4]