Mess Creek, formerly known as Mestua, is a tributary of the Stikine River in northwestern British Columbia, Canada.

[1][4] The northern half of Mess Creek forms a western boundary of Mount Edziza Provincial Park which lies within the traditional territory of the Tahltan people.

[5][6] Mess Creek's watershed covers 2,330 km2 (900 sq mi) and its estimated mean annual discharge is 59.3 m3/s (2,090 cu ft/s).

[17] Mess Creek flows through a long and narrow graben-like depression bounded by steeply-dipping faults that extend to the north.

The downthrowing of this fault during the Holocene may have been due to the draining of magma chambers following eruptions at the Mount Edziza volcanic complex.

Discharge at these hot springs may be linked to shallow hydrothermal systems driven by residual magmatic heat as they are adjacent to The Ash Pit, a recently active eruptive centre of the Mount Edziza volcanic complex.