[5] Methyl isonicotinate, a patented 4-pyridyl carbonyl compound, was found to be a useful semiochemical that does not use any type of pheromone.

No specific history was found on the compound, other than that research has been performed to investigate how this chemical can be used for the management of thrip-pests.

Methyl isonicotinate is the active ingredient in for example LUREM-TR (Koppers biological systems) and is used to detect a pest in an early stage.

[5] The addition of methyl isonicotinate to thrip control methods can increase the success of the trap.

Usage of methyl isonicotinate in traps can increase the catches up to 20 times depending on the species and the conditions.

[10] In the studies on acute toxicity of methyl isonicotinate, the effects were observed in vivo in rodents.

Based on the studies supported by Tsarichenko (1977), U.S. Library of Medicine (2017) and Gestis Substance Database (2017), Sprague-Dawley male and female rats were treated with methyl isonicotinate by oral gavage route.

[3] According to the estimated LD50 of 3906 mg/kg, methyl isonicotinate is classified as category V on GLP criteria for acute oral toxicity.

[10] Category V substances are identified as causing relatively low acute toxicity hazard.

[3] The dermal toxicity was estimated based on a study supported by Cosmetic ingredient review (2005) on methyl isonicotinate.

Furthermore, as mentioned before, the compound can serve as a semiochemical in thrips, affecting their movement and therefore increasing the functionality of traps.