Methylecgonine cinnamate is a natural tropane alkaloid found within the coca plant.

It is pharmacologically inactive,[2] but some studies funded by anti-drug agencies imply that it is active when smoked.

[citation needed] Furthermore, the discovery of differing impurity products yielding methylecgonine cinnamate in confiscated cocaine have led enforcing agencies to postulate that illicit manufacturers have changed their oxidation procedures when refining cocaine from a crude form.

[3] Methylecgonine cinnamate can dimerize to the truxillic acid derivative truxilline.

[2] Methylecgonine cinnamate is mentioned in patents of active cocaine analogue structures.