Through the 2015 season, South leads the series with a 27-11-1 record, including 14 consecutive victories in the Thanksgiving matchup.

[18] The football team won the Central Jersey Group IV state sectional title in 1983, 1986 and 1996.

[20] The 1996 team beat J. P. Stevens High School by a score of 27–12 to win the Central Jersey Group IV championship game and end the season 7-2-1.

[21] The team won the Central Jersey Group IV title in 1996 with a 33–8 win in the championship game played at Giants Stadium against the previously undefeated Hillsborough High School team led by future NFL player Shawn Mayer.

The team won the Shore Conference Championship in 2022 and fell short in the Handchen Cup game of the 2022 season.

[30] The girls' soccer team won the 2005 Central, Group IV state sectional championship, edging Brick Memorial High School by a 2–1 score in the tournament final.

[31] The boys cross country running team won the Group III state championship in 2013.

[32] The baseball team won Group III state championship in 2022, defeating Cranford High School by a score of 5-4 in the finals to finish the season with a record of 21-10.

The tent outside (the Middletown High School North Bubble) has remained, and is used to house sporting events.

For the last six years, the Middletown North Student Council has hosted the annual Megan Biebel Memorial SIDS game to benefit research for Sudden Infant Death Syndrome.

The event has raised over $100,000, and has attracted support from celebrities including singer Jon Bon Jovi.

2007 will bring the "North Carnival," which will be the traditional SIDS event, but raising money for brain cancer charities.

Notable events hosted at the MHSN PAC, and open to the public, include: For several years Comcast Cable has run the student produced series North in Action, which features student made movies, comedy sketches, music, and news.

New television series are continuously produced within the Middletown High School North TV production center.

The studio serves as the main production location for Middletown's Public-access television cable TV station on Comcast channel 20.