He played college football for the Florida Gators, was a member of a BCS National Championship team, and earned All-American honors.

He was selected by the Miami Dolphins in the first round of the 2011 NFL draft, and also played for the Los Angeles Chargers.

After his junior season in 2009, Pouncey was named an Associated Press honorable mention All-Southeastern Conference (SEC) selection and a Pro Football Weekly first-team All-American.

[7] Pouncey graded out as the top center and guard prospects in the 2011 NFL draft.

[12] In February 2014, the NFL released the "Wells Report" finding that Pouncey, along with Dolphins teammates Richie Incognito and John Jerry, had bullied and harassed lineman Jonathan Martin, another unnamed player, and an assistant trainer.

[15] Pouncey underwent hip surgery to repair a torn labrum with an expected recovery time of three months on June 23.

[17] Pouncey only played in five games in 2016 after dealing with a hip injury before being placed on injured reserve on December 13, 2016.