Milker's nodules are a cutaneous condition that is most commonly transmitted from the udders of infected cows.

[1]: 393 [2] Milker's nodule is caused by Paravaccinia virus.

[citation needed] Milker's nodules is a zoonotic dermatosis.

It was caused by double-stranded DNA virus of the Parapoxvirus genus.

Parapoxvirus usually presents in the saliva, nasal secretions, and in lesions over the udder, trunk, and limbs of affected bovine cattle.