Milton Creek, is a waterway in Columbia County, Oregon, United States.

It is 28.5 miles (45.9 km) long, rising in the Oregon Coast Range and emptying into Scappoose Bay – a slough of Multnomah Channel – one of the distributaries of the Willamette River where it enters the Columbia River.

[6] Portions of Milton Creek have been significantly altered since permanent settlement came to the region for both farming and transporting logs.

The lower 2 miles (3.2 km) originally flowed into the Columbia River through Jackass Canyon to the north of the courthouse in St. Helens but was relocated to its present path in 1861.

Scappoose Bay and Multnomah Channel was later lined with levees to protect from flooding.