Minnesota State Highway 172 (MN 172) is a 11.515-mile-long (18.532 km) highway in far northern Minnesota, which runs from its intersection with State Highway 11 at Baudette and continues north to its northern terminus in Wheeler's Point at the Lake of the Woods.

Highway 172 generally follows the Rainy River from Baudette to the Lake of the Woods.

State Highway 172 serves as a north–south route between Baudette, Hackett, Wheeler's Point, and the Lake of the Woods.

Zippel Bay State Park is located 6 miles west of the Wheeler's Point junction of Highway 172 and County Road 8.

The section of 172 (as 72) between County Road 6 and Wheeler's Point was paved by 1953.