The route was extended west to Centreville, and was removed from the state highway system in 1967.

As of 1965, the route was located in eastern Wilkinson and western Amite counties.

[2] MS 572 began at the center of Centreville, near a railroad track.

[1] Continuing eastward, the route exited Centreville and crossed over Beaver Creek and emerged into the village of Olio.

Lower Centreville Road continued east, concurrent with MS 569.