MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.
This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli.
This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells.
Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation.
[6] Mitogen-activated protein kinase 9 has been shown to interact with: This article incorporates text from the United States National Library of Medicine, which is in the public domain.