Primary villains include Mojo Jojo, an intelligent, megalomaniacal ape; HIM, a demonic being; Fuzzy Lumpkins, a Bigfoot-like hillbilly; Princess Morbucks, a wealthy, spoiled girl; the Gangreen Gang, a group of green-skinned hoodlums; Sedusa, a Gorgon-like seductress; the Amoeba Boys, a trio of dimwitted amoebas, and the Rowdyruff Boys, the Powerpuff Girls' evil male counterparts.
After a name change and character redesigns, a new pilot, "The Powerpuff Girls: Meat Fuzzy Lumpkins", aired on Cartoon Network's World Premiere Toons animation showcase in 1995.
In June 1991, Craig McCracken, then a student of the animation program of CalArts,[1] created a drawing of three girls on a sheet of orange construction paper as a birthday card design for his brother.
[7] The Powerpuff Girls have large eyes, inspired by Margaret Keane's art,[8] and stubby arms and legs with no visible digits.
McCracken preferred that they appear symbolic of actual girls rather than having a "realistic" look, meaning fewer body parts were needed.
[9] Blossom (voiced by Cathy Cavadini) is one of the three main protagonists and the self-proclaimed leader of the Powerpuff Girls; as the most level-headed and intelligent of the group, she also serves as strategist.
As shown in The Powerpuff Girls Movie, she was named for having spoken freely and honestly to the Professor shortly after her creation.
Though kind, she is a capable fighter and can understand various languages, including that of animals, and create powerful sonic blasts.
Buttercup (voiced by E. G. Daily in the original series, Natalie Palamides in the reboot) is one of the three main protagonists, who is described as a "tough hotheaded tomboy".
[citation needed] Narrator (voiced by Tom Kenny in the series, Craig McCracken in Whoopass Stew, Ernie Anderson in What a Cartoon!)
Mojo Jojo (voiced by Roger L. Jackson) is a highly intelligent chimpanzee and the Powerpuff Girls' archenemy.
He was formerly Professor Utonium's lab assistant before being exposed to Chemical X and gaining intelligence in the same accident that created the Powerpuff Girls.
Fuzzy Lumpkins[13] (voiced by Jim Cummings) is a pink, furry hillbilly monster who speaks in a southern accent and lives in the woods neighboring Townsville.
Her father, "Daddy" Morbucks, dotes on her and indulges in her whims, but it is implied that his patience is limited and Princess fears truly angering him.
The Rowdyruff Boys are the Powerpuff Girls' evil male counterparts, created by Mojo Jojo using a mixture of "snips, snails, a puppy dog tail", and radioactive toilet water, and possess the same powers as them.
The Derbytantes (voiced by Kate Higgins) are a group of roller skaters who enjoy playing Deathball, a sport similar to dodgeball and rollerball.
Manboy (voiced by Maurice LaMarche) is a short man who possesses superhuman strength and a magical, prehensile beard.
He was originally a lonely kid who built toy robots to keep him company, vowing revenge against the Powerpuff Girls after they accidentally destroyed them.