Moscazzano (Cremasco: Muscasà) is a comune (municipality) in the Province of Cremona in the Italian region Lombardy, located about 45 kilometres (28 mi) southeast of Milan and about 30 kilometres (19 mi) northwest of Cremona.

Moscazzano borders the following municipalities: Bertonico, Credera Rubbiano, Montodine, Ripalta Cremasca, Ripalta Guerina, Turano Lodigiano.

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