Motta d'Affermo (Sicilian: Motta d'Affermu) is a comune (municipality) in the Province of Messina in the Italian region Sicily, located about 80 kilometres (50 mi) east of Palermo and about 110 kilometres (68 mi) west of Messina.

Motta d'Affermo borders the following municipalities: Pettineo, Reitano, Tusa.

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