[4] The mountain is part of the Cascade Range and is situated in the Mount Baker-Snoqualmie National Forest.

Topographic relief is significant as the summit rises 4,160 feet (1,270 meters) above Anderson Creek in 0.8 mile (1.3 km).

[3] Mount Persis is located in the marine west coast climate zone of western North America.

As a result, the west side of the North Cascades experiences high precipitation, especially during the winter months in the form of snowfall.

[3] Due to its temperate climate and proximity to the Pacific Ocean, areas west of the Cascade Crest very rarely experience temperatures below 0 °F (−18 °C) or above 80 °F (27 °C).