[1] MNV is commonly used in research to model Human norovirus[2] because the latter is difficult to grow in the laboratory.

Standardized cell cultures are used in MNV propagation and the virus naturally infects mice, which allows studies in animal systems.

This additional reading frame encodes a virulence factor (VF1) which regulates the innate immune response.

This receptor, CD300lf, is a membrane glycoprotein, that functions in regulation of multiple immune responses.

In mice however, CD300lf functions in virus binding[11] thus having a role to play in the first steps of viral entry.