Mutěnice is a municipality and village in Hodonín District in the South Moravian Region of the Czech Republic.

The Kyjovka River flows through the eastern part of the municipality and supplies a system of fishponds there.

From 1312, the area of Mutěnice and neighbouring Čejkovice belonged to Knights Hospitaller.

It was built in the Baroque style in 1769–1775 by order of Empress Maria Theresa on the site of a former desolated chapel.

[8] Mutěnice is known for búdy, which are above-ground wine cellars and presses of folk architecture.