The encoded protein is likely to be a nuclear transcription factor.

[7] The expression of Nkx2-2 is regulated by an antisense RNA called Nkx2-2as.

[8] In the developing spinal cord, Nkx-2.2 regulates IRX3 thereby contributing to the proper differentiation of the ventral horn neurons.

[9] This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 20 is a stub.