[2] The river empties into the narrow Napetipi Bay which reaches inland for about 7 kilometres (4.3 mi) between high rocky shores.

[4] The Dictionnaire des rivières et lacs de la province de Québec (1914) says, Situated in Canadian Labrador, between the Saint Augustin River and the Eskimo River.

Jacques Cartier named the river Fleuve Saint-Jacques and caught many salmon here during his first voyage.

[5] The Napetipi River basin covers 1,262 square kilometres (487 sq mi).

[7] A map of the ecological regions of Quebec shows the Napetipi River in sub-regions 6o-T, 6n-T and 6m-T of the east spruce/moss subdomain.

[1] The river basin include part of the proposed Basses Collines du Lac Guernesé Biodiversity Reserve.

[1] The basin is home to mammals such as black bear, moose, wolf, American mink and red fox.

[2] The river had exceeded its target for salmon management, and in July 2018 the Ministry of Forests, Wildlife and Parks announced that in August anglers could keep their catch of one large salmon 63 centimetres (25 in) or longer in the Gros Mécatina, Napetipi, Saint-Paul, Vieux Fort and Matapedia rivers.