Neo Souli (Greek: Νέο Σούλι) is a village in Serres regional unit of Central Macedonia, located 7 km east of Serres.

At the southeastern end of Neo Souli, on the "Agrianista" hill, has been found an ancient settlement, with continuous habitation from prehistoric to modern years.

[2] In Roman times the settlement belonged to the territory ("chora") of the city of Sirra (modern Serres), from which it was administratively dependent.

[3] South of Neo Souli the ancient necropolis was extended, where various archaeological findings (vases, reliefs, coins etc.)

were found, as well as Greek inscriptions of the Roman imperial period.