2QL2476018012ENSG00000162992ENSMUSG00000034701Q13562Q60867NM_002500NM_010894NP_002491NP_035024Neurogenic differentiation 1 (Neurod1), also called β2,[5] is a transcription factor of the NeuroD-type.

[6] It is a member of the Neurod family of basic helix-loop-helix (bHLH) transcription factors, composed of Neurod1, Neurod2, Neurod4, and Neurod6.

It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus in mouse models and in human clinical patients.

[7] Neurod1 is found to convert reactive glial cells into functional neurons in the mouse brain in vivo[8] In the adult cortex, Neurod1 expression is a marker of mature excitatory pyramidal neurons in the upper-most layers of the cortex.

[12] This article incorporates text from the United States National Library of Medicine, which is in the public domain.