It was extended to its present length by the following year and realigned to serve Harford later in the decade.

The route progresses northward through a small hamlet, crossing the Owego and Harford Railway and serving a mobile home park.

The highway soon reverts to a southeast direction, passing to the north of Beaver Pond and the county line, while NY 221 enters the hamlet of Hunts Corners and intersects with CR 136 (Jennings Creek Road).

It bypasses the nearby hamlet of Clarks Corner and soon intersects with the eastern terminus of CR 133, which gives way to NY 221 as the state road merges with the east–west county highway.

[3] Within the village, the route gains the West Main Street moniker and heads through a mix of residential and commercial areas.

After the exit from I-81, NY 221 reenters another rural area and turns eastward past Dean Pond.

Each end of SH 1075 connected to the segment of the loop route between modern NY 38 and Owego Hill Road, which was rebuilt as part of an earlier project awarded on September 19, 1906, and included in the state highway system on July 5, 1908, as SH 379.