He played college football at William & Mary before transferring to South Carolina.

Muse grew up in Belmont, North Carolina, and attended South Point High School.

[2] Muse was named third-team All-Colonial Athletic Association as a sophomore after finishing the season with 30 receptions for 453 yards and one touchdown.

[5] Muse decided to utilize the extra year of eligibility granted to college athletes who played in the 2020 season due to the coronavirus pandemic and return to South Carolina for a third season.

On January 22, 2025, the Philadelphia Eagles signed Muse to their practice squad.