Spitzer is the editor and co-writer of numerous books, including Public Folklore and Blues for New Orleans: Mardi Gras and America’s Creole Soul.

[4][6] Spitzer was hired by the Smithsonian to help plan the 1976 United States Bicentennial Festival.

[4][8] After leaving Philadelphia, Spitzer spent time in Louisiana, where he learned more about the state's music and culture.

[4] While studying for his doctorate in Austin, Texas, he worked at KOKE-FM[9] and as a host and producer at NPR affiliate KUT-FM.

[9] He founded the Louisiana Folklife Program and helped develop the Baton Rouge Blues Festival.

[1] Spitzer was diagnosed with cancer in 1979, and underwent multiple rounds of chemotherapy and stays at Baton Rouge General Hospital; he entered remission in 1980.

[7] Following the hurricane, Spitzer was vocal about the need for recovery to focus on cultural elements of New Orleans, including music and food.