He made his senior international debut later that month, placing fourth at Trophée Métropole Nice Côte d'Azur.

He stepped onto his first senior international podium in December, taking gold at the Santa Claus Cup in Hungary.

[6] Following the withdrawal of Matteo Rizzo, Italy selected Memola to skate at the 2022 European Championships in Tallinn, Estonia.

[7] Competing in his first ISU Championship, he qualified for the final segment by placing twelfth in the short program and finished fifteenth overall.

Memola's results qualified him for the 2022–23 Junior Grand Prix Final, which he stated he was particularly "happy" about as the event was being held in Italy that year.

This was the first Junior Grand Prix Final title for an Italian man and the first for Italy in any discipline since the ice dance team Faiella/Milo in the inaugural 1997–98 edition.

"[12] Shortly after the Junior Grand Prix Final, Memola attended his first senior national championships and won the silver medal.

Memola did not attempt any quadruple jumps during the free program, having found them insufficiently secure in practice that day and not wanting to risk it.

Memola called it "amazing" to reach the top ten in his first appearance at the championships, and cited the importance of having done so to retain Italy's second entry in the men's event for the following year.

He was fifth after the short program; in the free skate, he landed two quadruple Lutz jumps and rose to second place to win the silver medal.