Niobium(V) bromide is the inorganic compound with the formula Nb2Br10.

[2] It is a diamagnetic, orange solid that hydrolyses readily.

The compound adopts an edge-shared bioctahedral structure, which means that two NbBr5 units are joined by a pair of bromide bridges.

Niobium(V) bromide can be prepared by the reaction of bromine with niobium metal at 230-250 °C in a tube furnace.

It can also be produced from the more accessible oxide by metathesis using aluminium tribromide:[4] A challenge with the latter method is the occurrence of NbOBr3 as an impurity.